October 21, 2025

The Evolving Pillar Two Landscape: Strategies for Multinationals in a Changing Tax World

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On October 21st, Mayer Brown and Loyens & Loeff hosted a webinar exploring the latest developments and implications of Pillar Two for multinational organizations. The program provided valuable insights into the evolving global tax landscape, highlight key considerations for US-based groups, and offer practical guidance to help your organization navigate upcoming changes.

Topics included:

  • The US Treasury/G7 Agreement on a side-by-side system for US multinational groups: mechanics; open questions; possible changes to treatment of substance-based non-refundable tax credits; challenges to implementation in EU member states and other countries
  • Pillar Two simplification and safe harbors
  • The future of Pillar Two
  • Potential re-introduction of US retaliatory taxes (Section 899) if the side-by-side system is not implemented

For additional information, please contact Kaela Milewski at kmilewski@mayerbrown.com or Shilpa Patel at spatel@mayerbrown.com.

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